of a hardware-virtualized guest OS. Such DRM is ultimately toothless, of course, because the host can always be modified to grab perfect digital copies of the audio, video, or whatever is coming out of the guest.
How would you get a "perfect digital copy" of a PDF/ePUB/... from the video output? At best you'd get a sequence of raster images, which is a far cry from a perfect digital copy.
Stefan